SARS-CoV-2: Infection induces antibodies capable of killing infected cells regardless of disease severity

Researchers demonstrated that SARS-CoV-2 infection induces polyfunctional antibodies. Beyond neutralization, these antibodies can activate NK cells or the complement system, leading to the destruction of infected cells. Polyfunctional antibodies were found in all individuals (symptomatic and asymptomatic). These findings show that infection induces antibodies capable of killing infected cells regardless of the severity of the disease.

Those who had COVID-19 may only need one vaccine dose, study suggests

Those recovered from COVID-19 had a robust antibody response after the first mRNA vaccine dose, but little immune benefit after the second dose, according to new research. The findings suggest only a single vaccine dose may be needed to produce a sufficient antibody response. Those who did not have COVID-19 did not have a full immune response until after receiving their second vaccine, reinforcing the importance of the two recommended doses.