A multidisciplinary research team has provided fundamental new insight into the mechanism of the medical drug dimethyl fumarate, which is the active component of important treatments for multiple sclerosis and psoriasis. The results contribute to the d…
How do pelvic floor muscle exercises reduce overactive bladder symptoms?
Overactive bladder (OAB) is a common form of urinary incontinence that is widely treated with pelvic floor muscle (PFM) training. A new laboratory study lends insights into how PFM training works: by reducing contractions of the detrusor muscle of the …
MS genes formerly missing-in-action have been found
Scientists have cracked a tough nut in multiple sclerosis: where are all the genes?
Conceptual framework to study role of exercise in multiple sclerosis
Researchers have proposed a conceptual framework for examining the relationship between exercise and adaptive neuroplasticity in the population with multiple sclerosis (MS).
Environmental factors may trigger onset of multiple sclerosis
A new study finds that certain environmental conditions like salt concentrations and temperature may precipitate structural changes that take place in myelin sheaths in the onset of multiple sclerosis (MS). Myelin sheaths are the ‘insulating tape’ surr…
New immunotherapy targeting blood-clotting protein
A team has developed an antibody that blocks the inflammatory and oxidative activity of fibrin, which contributes to neurodegeneration in the brain, without compromising the protein’s clotting function.
Link between gut flora and multiple sclerosis discovered
In multiple sclerosis, a defective response of the body’s own immune system leads to brain tissue damage. Gastrointestinal microbiota could play a far greater role in the pathogenesis of the disease than previously assumed.