The permanent neurological deficits of multiple sclerosis patients largely depend on the extent of degeneration of long nerve fibers. The latter is initiated by ruptures in the cell membrane and the resulting influx of calcium ions.
Study sheds light on brain cell changes in people with MS
Fresh insights into the types of cells found in the brains of people with multiple sclerosis could help develop improved therapies, research has found. The study focused on cells in the brain that help to repair damage to nerve cells caused by the dise…
Multiple sclerosis: Helping cells to help themselves
Diseases such as multiple sclerosis are characterized by damage to the ‘myelin sheath’, a protective covering wrapped around nerve cells akin to insulation around an electrical wire. Researchers have discovered how the body initiates repair mechanisms …
Multiple sclerosis treatments delay progression of the disease
A new study finds multiple sclerosis treatments have long-term benefits, and that early treatment is important. The study is the first to provide evidence that the currently available therapies can delay progression of disability in Multiple Sclerosis….
New immune response regulators
Researchers have discovered new proteins that regulate T cells in the human immune system. Some of these proteins can provide possible new targets for drug development in treating immune-mediated diseases.
Stroke drug may also prevent Alzheimer’s disease
Researchers have discovered that a drug currently being developed to treat stroke patients could also prevent Alzheimer’s disease. The study shows that the genetically engineered protein 3K3A-APC protects the brains of mice with Alzheimer’s-like sympto…
Newly discovered leukodystrophy in children: Potential cure
Medical researchers have uncovered a novel disease of children affecting the brain white matter — the myelin sheath –, leading to severe incapacity and death in some cases. These defects were corrected by a treatment with fingolimod, a drug in use fo…