Chronic stress is associated with the pathogenesis of psychological disorders such as depression. A study is the first to identify the role of a neuronal receptor that straddles the intersection between social stress, inflammation, and anxiety in roden…
Cognitive behavior therapy tops other psychotherapies in reducing inflammation
A review of 56 randomized clinical trials finds that psychological and behavioral therapies may be effective non-drug treatments for reducing disease-causing inflammation in the body.
Impact of COVID-19 infection in blood cancer patients
Researchers report on one of the first studies to investigate the outcome of COVID-19 infection in patients with blood cancer.
Immune cells multiply and diversify in mouse lungs at birth
An explosion in the number and types of immune cells in the lungs of newborn mice likely helps them adapt to breathing and protects them from infection, says a new study.
Human lifelong immunity depends on APRIL
Researchers have identified the protein APRIL as a key regulator of plasmacyte maintenance and immunoglobulin production in humans. They showed in a patient with common variable immunodeficiency and a mutation in the gene encoding APRIL that a lack of …
A better model for neutrophil-related diseases
Neutrophils are critical immune cells for antimicrobial defense, but they can exacerbate a number of diseases, perhaps including COVID-19. The traditional approaches to study neutrophils in animal models are limited in specificity and effectiveness. Sc…
A boost for cancer immunotherapy
MIT engineers have found a way to boost the effectiveness of cancer immunotherapy drugs called checkpoint inhibitors. They showed that if they treated mice with these drugs along with new nanoparticles that stimulate the immune system, the therapy beca…
Cancer cells cause inflammation to protect themselves from viruses
Researchers have uncovered how cancer cells protect themselves from viruses that are harmful to tumors but not to healthy cells. These findings could lead to improved viral treatments for the disease.