People with gluten sensitivity have an antibody profile that differs from that of people with celiac disease, which could help doctors diagnose gluten sensitivity.
Insight on how to build a better flu vaccine
Repeated exposure to influenza viruses may undermine the effectiveness of the annual flu vaccine. A team of researchers has developed an approach to assess whether a vaccine activates the kind of immune cells needed for long-lasting immunity against ne…
Microgel immuno-acceptance method could improve pancreatic islet transplant success
Researchers have developed a new microgel drug delivery method that could extend the effectiveness of pancreatic islet transplantations — from several years to possibly the entire lifespan of a recipient.
Strokes in babies are surprisingly common; here’s how the body rushes to the rescue
New research is shedding light on the development of the brain’s immune defenses – and how those defenses respond to strokes that strike one in 4,000 babies in the first month of life.
Antibody blockade effective in treatment of severe COVID-19
Researchers find an overlap in the pathogenesis of cytokine release syndrome and COVID-19, and show that the symptoms of both can be alleviated by IL-6 signaling blockade.
Giant nanomachine aids the immune system
In order to kill diseased cells, our immune system must first identify them. The so-called peptide-loading complex plays a key role in this process. A research team has analyzed this nanomachine in atomic detail.
Beating HIV and COVID-19 may depend on tweaking vaccine molecules
In a new study, researchers show that one way to improve the body’s immune response to vaccines is to factor in antigen valency. Valency refers to the number of antibody binding sites on an antigen.
Prior Zika virus infection increases risk of severe dengue disease
A new study finds that people who have antibodies to the mosquito-borne Zika virus are more vulnerable to developing dengue disease. This immune interaction, called antibody-dependent enhancement, could complicate the search for a safe and effective va…
Mosquito immune system mapped to help fight malaria
Scientists have created the first cell atlas of mosquito immune cells, to understand how mosquitoes fight malaria and other infections. Researchers discovered new types of mosquito immune cells, including a rare cell type that could be involved in limi…
Breakthrough in using stem cells to treat enteric nervous system disorders
Scientists have made a breakthrough in understanding how the enteric nervous system forms, which could pave the way for new treatments for neurodegenerative diseases such as Parkinson’s.