Since the late 1990s, immunotherapy has been the frontline treatment against lymphomas where synthetic antibodies are used to stop the proliferation of cancerous white blood cells. However, in the more than 20 years since their use began, the molecular…
MS drug may be used to inhibit HIV infection and reduce latent reservoir
A multiple sclerosis drug may be used to block HIV infection and reduce the latent reservoir, according to new research.
Single-cell analysis provides new insights into mitochondrial diseases
Investigators have made discoveries at the single cell level to uncover new details concerning mitochondrial diseases — inherited disorders that interfere with energy production in the body and currently have no cure.
Virus uses decoy strategy to evade immune system
Researchers have learnt more about how viruses operate and can evade the immune system and are now using their discovery to help learn more about COVID-19.
‘Reelin’ in a new treatment for multiple sclerosis
In an animal model of multiple sclerosis (MS), decreasing the amount of a protein made in the liver significantly protected against development of the disease’s characteristic symptoms and promoted recovery in symptomatic animals, scientists report.
Study provides insights into how Zika virus suppresses the host immune system
A research team has outlined how the Zika virus, which constituted an epidemic threat in 2016, suppresses the immune system of its host. The work provides valuable structural and functional information on the interaction between ZIKV and its host and o…
Internal differences: A new method for seeing into cells
The new technology may help answer outstanding questions about the immune system, cancer, Alzheimer’s, and more.
Immunotherapy-resistant cancers eliminated in mouse study
In a mouse study, researchers have found that an antibody that targets the protein TREM2 empowers tumor-destroying immune cells and improves the effectiveness of cancer immunotherapy.
Study reveals immune-system paralysis in severe COVID-19 cases
A new study shows that in severely ill COVID-19 patients, ‘first-responder’ immune cells, which should react immediately to signs of viral or bacterial presence in the body, instead respond sluggishly.
Protein uses two antiviral strategies to ward off infections
To protect humans against infection, a protein called MARCH8 tags the vesicular stomatitis virus (VSV) for destruction while it merely holds HIV hostage, a new study shows.