Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate. Scientists have examined the corresponding genes of the helper proteins in a large study.
Researchers expose power of enzyme on key immune cells
Communication, serendipity and an enzyme called DOT1L have all combined to produce some exciting findings into the immune system’s B cells and T cells. These findings could result in further studies into a target for asthma and allergies, and fundament…
Immune cell that drives breast cancer could be effective target in novel immunotherapies
Researchers have identified a type of immune cells that acts as a major driver of breast cancer growth by preventing the accumulation of a specific protein that induces anti-tumor responses. This new knowledge could be utilized for the development of n…
Drug may boost vaccine responses in older adults
A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults, a new study shows.
New combination therapy could help fight difficult-to-treat cancers with common mutations
Scientists describe a new combination therapy that suppresses the MAPK pathway by holding cancer-driving proteins in a death grip. This combination of two small molecules has the potential to treat not only BRAF mutated melanoma but also additional agg…
Drugs create balancing act for patients with non-small cell lung cancer
Researchers identified a correlation between multisystem immune-related adverse events and improved rates of survival. This new information will be helpful in discussing with patients the spectrum of immune side effects that may occur from immunotherap…
Remdesivir likely to be highly effective antiviral against SARS-CoV-2, study finds
The drug remdesivir is likely to be a highly effective antiviral against SARS-CoV-2, according to a new study. Researchers describe giving the drug to a patient with COVID-19 and a rare immune disorder, and observing a dramatic improvement in his sympt…
STAT-5 molecule holds promise to reprogram white blood cells for better cancer treatment outcome
Researchers report that CAR T cells can stay active longer and mediate tumor killing more effectively when STAT5, a key signaling molecule, is kept in an active form within CAR T cells.
tRNA fragments are involved in post-stroke immune reactions
Following a stroke, the immune system triggers an inflammatory reaction that can either overshoot or turn into an immune deficiency. Now, a team of researchers has shown that tRNA fragments play a role in this immune reaction. Fragments of tRNAs, which…
New analysis method for predicting the risks and effects of immunotherapy
In a new study, researchers have been able to show differences in how Rituximab, a monoclonal antibody drug, interacts with the blood of healthy individuals compared to patients with chronic lymphatic leukemia. This has awakened hopes that this analysi…