Researchers have found that people with sepsis have never-before-seen particles in their blood. The scientists are the first to show that these particles, called elongated neutrophil-derived structures (ENDS), break off of immune cells and change their…
Genetically engineered T cells could lead to therapies for autoimmune diseases
Immunobiologists have created a five-module chimeric antigen receptor T cell that is showing early potential to fight Type 1 diabetes.
Medicine-carriers made from human cells can cure lung infections
Scientists used human white blood cell membranes to carry two drugs, an antibiotic and an anti-inflammatory, directly to infected lungs in mice. The nano-sized drug delivery method successfully treated both the bacterial growth and inflammation in the …
Research reveals how a fungal infection activates inflammation
Scientists have shed light on the mechanisms that underlie how Aspergillus fumigatus activates the inflammasome, with implications for therapeutic development.
Differences in immunity and blood vessels likely protect children from severe COVID-19
Differences in the immune systems and better blood vessel health were among the factors protecting children from severe COVID-19, according to a new review.
For people with certain BRCA mutations, activating the immune system could be promising treatment
Tumors with mutations in the BRCA2 cancer-predisposition gene respond better to checkpoint blockade immunotherapy than tumors with mutations in BRCA1, scientists have found.
Scientists discover role of protein in detecting the common cold virus
The role of a protein in detecting the common cold virus and kickstarting an immune response to fight infection has been uncovered by a team of scientists.
Why long-suffering hosts grow a thick skin
Occasionally, following a transplant procedure, the donor’s immune cells recognize the recipient’s tissues as foreign and trigger a multisystem disorder called graft-versus-host disease (GVHD). Occurring commonly after bone marrow or stem cell transpla…
Cancer-killing virus: Activates immune system against colon cancer
A cancer-killing virus that scientists developed could one day improve the immune system’s ability to eradicate tumors in colon cancer patients, reports a new study. The preclinical research is a first step to showing that oncolytic virus CF33 can targ…