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Month: February 2021

How SARS-CoV-2’s sugar-coated shield helps activate the virus

February 25, 2021 Immune System News -- ScienceDaily

SARS-CoV-2, the virus that causes COVID-19, is coated with sugars called glycans, which help it evade the immune system. New research shows precisely how those sugars help the virus become activated and infectious and could help with vaccine and drug d…

Posted in MS Wire
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Scientists reveal details of antibodies that work against Zika virus

February 25, 2021 Immune System News -- ScienceDaily

The Zika outbreak of 2015 and 2016 is having lasting impacts on children whose mothers became infected with the virus while they were pregnant.

Posted in MS Wire
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Sulfur metabolism may have paved the way for evolution of multicellularity

February 24, 2021 Immune System News -- ScienceDaily

When the slime mold Dictyostelium discoideum runs out of food, sulfur limitation drives its development from a unicellular to a multicellular organism. Researchers now present the nutrient signaling pathways in this early eukaryote in great detail. The…

Posted in MS Wire
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Mechanism by which exercise strengthens bones and immunity

February 24, 2021 Immune System News -- ScienceDaily

Scientists have identified the specialized environment, known as a niche, in the bone marrow where new bone and immune cells are produced. The study also shows that movement-induced stimulation is required for the maintenance of this niche, as well as …

Posted in MS Wire
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How to neutralize the SARS-CoV-2 virus

February 24, 2021 Immune System News -- ScienceDaily

In the absence of effective treatments for COVID-19, many countries have approved the therapeutic use of blood plasma from recovering patients because it contains antibodies against the coronavirus. But not every type of antibody can neutralize the vir…

Posted in MS Wire
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Discovery offers potential for stripping tumors of T cell protection

February 24, 2021 Immune System News -- ScienceDaily

Researchers have discovered a mechanism that tumors use to switch on protective regulatory T cells, raising the potential for drug treatments that render tumors more vulnerable to cancer immunotherapy.

Posted in MS Wire
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Human lung and brain organoids respond differently to SARS-CoV-2 infection in lab tests

February 24, 2021 Immune System News -- ScienceDaily

Researchers are using stem cell-derived organoids to study how SARS-CoV-2 interacts with various organ systems. Their findings may help explain the wide variety in COVID-19 symptoms and aid the search for therapies.

Posted in MS Wire
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Novel mechanism of resistance to T-cell bispecific antibodies and CAR-T targeting HER2 breast cancer

February 23, 2021 Immune System News -- ScienceDaily

Researchers report how HER2 breast cancer cells adopt a strategy to resist clearance by redirected lymphocytes. Findings evidence that the disruption of interferon-gamma signaling confers resistance to these immunotherapies and promotes disease progres…

Posted in MS Wire
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Turbocharging the killing power of immune cells against cancer

February 23, 2021 Immune System News -- ScienceDaily

Creating ‘super soldiers’ of specific white blood cells to boost an anti-tumor response has been shown in a series of elegant experiments.

Posted in MS Wire
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Innate immune system worsens the situation in severe COVID-19

February 23, 2021 Immune System News -- ScienceDaily

In patients with severe COVID-19, the innate immune system overreacts. This overreaction may underlie the formation of blood clots and deterioration in oxygen saturation that affect the patients, according to a new study.

Posted in MS Wire
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