A research group has succeeded in understanding why a very extended structure is important for an essential protein from the human immune system. The new results offer new opportunities for adjusting the activity of the immune system both up and down. …
Combination treatment for common glioma type shows promise in mice
Gliomas are common brain tumors that comprise about one third of all cancers of the nervous system. Researchers tested a novel combination treatment approach on mice with tumors with characteristics similar to human astrocytomas and found tumor regress…
Antibody-based COVID-19 treatments work best in concert with immune cells
Antibody-based drugs have been authorized for emergency use in COVID-19 patients by the Food and Drug Administration. Researchers have discovered that the ability to interact with other elements of the immune system is an indispensable part of the effe…
Asthma may heighten flu risk and cause dangerous mutations
A subtype of asthma in adults may cause higher susceptibility to influenza and could result in dangerous flu mutations. Animal studies have found that paucigranulocytic asthma (PGA) – a non-allergic form of the condition – allows the flu virus to flour…
Let the immune cell see the virus: Scientists discover unique way to target common virus
Scientists have discovered a unique way to target a common virus that affects one in 200 newborn babies in the UK but for which there is only limited treatments available.
To improve immunotherapy, researchers look to shift immune cells’ access to sugar
New research suggests that a way to improve immunotherapy is by altering immune cells’ access to sugar.
TB study reveals potential targets to treat and control infection
Researchers may have found a new pathway to treat and control tuberculosis (TB), the disease caused by Mycobacterium tuberculosis (Mtb). Using single-cell RNA sequencing (scRNAseq), a next-generation sequencing technology, scientists were able to furth…
New immunotherapy target discovered for malignant brain tumors
Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body’s immune system. The discovery emerged from laboratory …
Immunotherapy — targeted drug combination improves survival in advanced kidney cancer
Patients with advanced kidney cancer, who received a targeted drug combined with a checkpoint-blocker immunotherapy agent had longer survival than patients treated with the standard targeted drug according to the results from a phase 3 clinical trial.
Main genetic causes of autoimmune Addison’s disease identified
Scientists have discovered the genes involved in autoimmune Addison’s disease.