Scientists have implicated a type of immune cell in the development of chronic lung disease that sometimes is triggered following a respiratory viral infection. The evidence suggests that activation of this immune cell serves as an early switch that, w…
Basic mechanisms that regulate HIV expression
Researchers conducted studies with yeast to screen a large library of human factors for binding to HIV deoxyribonucleic acid (DNA) sequences responsible for virus’ expression. As a result, they identified several factors as potential regulators and con…
Basic mechanisms that regulate HIV expression
Researchers conducted studies with yeast to screen a large library of human factors for binding to HIV deoxyribonucleic acid (DNA) sequences responsible for virus’ expression. As a result, they identified several factors as potential regulators and con…
New CAR T-Cell therapy extends remission in heavily relapsed multiple myeloma patients
A new type of CAR T-cell therapy more than triples the expected length of remission for multiple myeloma patients who have relapsed several times, according to an international clinical trial.
Immune cells in cerebrospinal fluid predict response to immunotherapy
Immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies.
New method facilitates development of antibody-based drugs
In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases. Now, researchers have developed a new, efficient method based on the genetic scissors CRISPR-Cas9, that facilitates antibody development.
HSC transplants in embryos: Opening the door for hematopoiesis research
Researchers describe a new technique for hematopoietic stem cell transplantation in embryos that does not require destroying host hematopoietic system.
New way to halt excessive inflammation
Researchers have discovered a new way to ‘put the brakes’ on excessive inflammation by regulating a type of white blood cell that is critical for our immune system.
Less inflammation with a traditional Tanzanian diet than with a Western diet
Urban Tanzanians have a more activated immune system compared to their rural counterparts. The difference in diet appears to explain this difference: in the cities, people eat a more western style diet, while in rural areas a traditional diet is more c…
Immune cells in blood influence the brain during early development of Parkinson’s disease
A group of people with sleep disorders have helped researchers make an important discovery about Parkinson’s disease. The study could pave the way for new diagnostic tools and forms of treatment in the future.