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Month: April 2021

Engineering T cells to attack cancer broadly

April 30, 2021 Immune System News -- ScienceDaily

This study builds on decades of work showing that the protein IL-24 attacks cancer broadly, and is the first to deliver the protein using T cells. This approach is in contrast to CAR-T cells, which are built to recognize proteins on the surface of canc…

Posted in MS Wire
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Shortage of DNA building blocks in the cell releases mitochondrial DNA

April 30, 2021 Immune System News -- ScienceDaily

Mitochondria are the energy suppliers of our body cells. These tiny cell components have their own genetic material, which triggers an inflammatory response when released into the interior of the cell. The reasons for the release are not yet known, but…

Posted in MS Wire
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Prior SARS-CoV-2 infection boosts response to variants after first vaccine dose

April 30, 2021 Immune System News -- ScienceDaily

A single dose of vaccine boosts protection against SARS-CoV-2 coronavirus variants, but only in those with previous COVID-19, a study has found.

Posted in MS Wire
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New atlas of genetic function maps complexities of immune system and immune diseases

April 29, 2021 Immune System News -- ScienceDaily

A new genetic database for autoimmune and autoinflammatory diseases will allow experts to more deeply understand how immune disorders develop and plan future drug discovery projects. Scientists also hope this atlas of immune-related genome data may eve…

Posted in MS Wire
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How meningitis-causing bacteria may sense fever to avoid immune killing

April 29, 2021 Immune System News -- ScienceDaily

Researchers have discovered a mechanism through which meningitis-causing bacteria can evade our immune system. In laboratory tests, they found that Streptococcus pneumoniae and Haemophilus influenzae respond to increasing temperatures by producing safe…

Posted in MS Wire
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How SARS-CoV-2 hijacks human cells to evade immune system

April 29, 2021 Immune System News -- ScienceDaily

Researchers discovered one way in which SARS-CoV-2 hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.

Posted in MS Wire
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New, rapid CRISPR/Cas9 method identifies key genes in zebrafish spinal cord regeneration

April 29, 2021 Immune System News -- ScienceDaily

A new, rapid screening approach uses CRISPR/Cas9 technology to identify immune system-related genes that play a crucial role in repairing zebrafish spinal cord injuries.

Posted in MS Wire
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Treating severe COVID-19 cases

April 27, 2021 Immune System News -- ScienceDaily

Long non-coding RNA molecules (lncRNAs) are potential regulators of anti-viral response during severe SARS-CoV-2 infection. Researchers constructed a gene co-expression network that measures the relationship of gene expression patterns across a group o…

Posted in MS Wire
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SARS-CoV-2 curtails immune response in the gut

April 27, 2021 Immune System News -- ScienceDaily

Scientists have provided further evidence of the gut’s role in COVID-19. They have transformed human intestinal cells into ‘mini guts’ to follow infection process.

Posted in MS Wire
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Common inflammatory bowel disease treatment blunts COVID-19 vaccine response, study finds

April 26, 2021 Immune System News -- ScienceDaily

People who take a commonly-prescribed drug for inflammatory bowel disease (IBD) should not assume they are protected after a first dose of COVID-19 vaccine, after a large-scale study found many had poor antibody responses.

Posted in MS Wire
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