Scientists have discovered stem cells of the hematopoietic system in glioblastomas, the most aggressive form of brain tumor. These hematopoietic stem cells promote division of the cancer cells and at the same time suppress the immune response against t…
Researchers engineer cells to destroy malignant tumor cells but leave the rest alone
Researchers have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors.
Bigger may not always be better: Density governs receptor activation on immune cells
Scientists have gained novel insights into how an important class of immune receptors called tumor necrosis factor receptors (TNFR) are activated.
Muscling up with nanoparticle-based anti-inflammatory therapy
Researchers have developed a new approach in which specifically designed anti-inflammatory nanoparticles (NPs) that could be applied locally and selectively to chronically inflamed muscles severely affected or at more immediate risk of deterioration, a…
How immune cells can be trained to fight infections
The body’s immune cells fight off microbes and other invaders, and can also be reprogrammed or ‘trained’ to respond even more aggressively to such threats, report scientists who have discovered the fundamental rule underlying this process in a particul…
Crucial insight into how Ebola virus evades our immune defenses
Researchers have discovered a key way that one of the world’s deadliest pathogens, Ebola virus, evades the immune system. Understanding this process provides new potential targets for the future development of anti-viral therapies for a disease.
Immunologists discover new trick used by MRSA superbug — may aid vaccine development
New research has uncovered a novel trick employed by the bacterium Staphylococcus aureus to thwart the immune response, raising hopes that a vaccine that prevents deadly MRSA infections is a little closer on the horizon.
Common plant fiber gel doubled rate of tumor eradication
Many people don’t realize that the trillions of bacteria, viruses, and fungi residing within the gastrointestinal tract –collectively called the gut microbiome — are connected to overall health, and specifically to cancer.
Roadmap to HIV eradication via stem cell therapy
A groundbreaking study found that stem cells reduce the amount of virus causing AIDS, boost the body’s antiviral immunity, and restore the gut’s lymphoid follicles damaged by HIV. It provided a roadmap for multi-pronged HIV eradication strategies.
‘Multi-kingdom dialogue’ between internal, external microbiota
Scientists have identified an internal communication network in mammals that may regulate tissue repair and inflammation, providing new insights on how diseases such as obesity and inflammatory skin disorders develop.