Researchers have found a way to reduce organ rejection following a transplant by using a special polymer to coat blood vessels on the organ to be transplanted. The polymer substantially diminished rejection of transplants in mice when tested. The disco…
New drug combo shows early potential for treating pancreatic cancer
A team of researchers has developed an immunotherapy strategy that can eliminate pancreatic tumors in mice. The new therapy, a combination of three drugs that boost the body’s immune defenses against tumors, is expected to enter clinical trials later t…
Cytokine increases production of ‘beige fat’ to burn more cellular energy
An immune signal promotes the production of energy-burning ‘beige fat,’ according to a new study. The finding may lead to new ways to reduce obesity and treat metabolic disorders.
Study reveals what triggers lung damage during COVID-19
Researchers found that a specific subtype of macrophages that originated from blood monocytes plays a key role in the hyper-inflammatory response in SARS-CoV-2 infected lungs, by performing single-cell RNA sequencing of bronchoalveolar lavage fluid cel…
Organoid bladders reveal secrets of UTIs
Scientists have developed two complementary bladder models to study urinary tract infections (UTIs) caused by E. coli: bladder organoids and a bladder-on-a- chip. The two studies reveal how bacteria invade the bladder, and how they evade the immune sys…
Researchers uncover a way to harness the power of immunotherapy for advanced prostate cancer
Researchers identified an inhibitor that showed promise against metastatic castration-resistant prostate cancer cells. From there, they continued to untangle the web to discover multiple levels of cellular processes that were preventing the immune syst…