Scientists show a causal link between tissue repair, mitochondrial metabolism, and the activation and function of macrophages (scavenger cells).
Tau and PQBP1: Protein interaction induces inflammation in the brain
Researchers have clarified the relationship between the intracellular receptor PQBP1 and the structural protein Tau, which is dysregulated in neurodegenerative diseases such as Alzheimer’s disease. Tau was found to interact with PQBP1 in immune cells o…
Reimagining immunity in the eye
Immune cells could be doing much more than we think in protecting our eyes — researchers uncover new details.
Trigger found for harmful inflammation in lupus, macular degeneration
Lupus, an autoimmune disease, and macular degeneration, a leading cause of vision loss, share a common contributor to harmful inflammation, researchers found.
How the body uses fat to fight infection
New research reveals how our immune cells use the body’s fat stores to fight infection. The research could help develop new approaches to treating people with bacterial infections. And the team say their work could one day help treat infections in vuln…
Research finds potential mechanism linking autism, intestinal inflammation
Moms infected during pregnancy who produce elevated levels of the cytokine IL-17a may have microbiome alterations that prime offspring for aberrant immune responses later in life, a mouse study suggests.
How SARS-CoV-2 evades our immune system
Scientists have identified a key mechanism used by the SARS-CoV-2 virus to evade host immune systems.
New marker for better assessing the severity of COVID-19
Researchers have found a new marker in the blood of COVID-19 patients. The finding provides insights into the course and development of the disease and could lead to better diagnoses.
Researchers find surprising benefit to the immune system following infection
The human body’s immune system weakens over time, making older adults more susceptible to infections and leaving scientists with the puzzling dilemma of how to maintain health across the lifespan. A recent study into how infection affects the immune sy…
Immune system-stimulating nanoparticle could lead to more powerful vaccines
Researchers designed a new nanoparticle adjuvant that may be more potent than others now in use. Studies in mice showed it significantly improved antibody production following vaccination against HIV, diphtheria and influenza.