Reactive electrophilic drugs like Tecfidera, approved for the treatment of relapsing multiple sclerosis, show a lot of potential but are also mystery. Scientists have now used an innovative chemical method to uncover the biological mechanisms of Tecfid…
New avenue for study of diseases like multiple sclerosis
A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination — when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between ne…
Brain molecule helps ‘wake up’ cells that could help tackle MS and similar diseases
An immunological molecule called fractalkine can boost the production of brain cells that produce myelin, a key factor in diseases such as multiple sclerosis, according to recent research.
Cognitive rehabilitation improves cognitive impairment in people with multiple sclerosis
Experts in MS research suggest that cognitive rehabilitation is an effective approach to improving MS-related cognitive impairment.
Discovery raises possibility of new medication for Alzheimer’s, Parkinson’s
Researchers have for the first time demonstrated it’s possible to use a synthetic thyroid hormone to regulate a gene implicated in neurodegenerative diseases like Alzheimer’s, Parkinson’s and multiple sclerosis.
Combining plant-based diet and healthy microbiome may protect against multiple sclerosis
A new study shows that a diet rich in isoflavone, a phytoestrogen or plant-based compound that resembles estrogen, protects against multiple sclerosis-like symptoms in a mouse model of the disease. Importantly, the isoflavone diet was only protective w…
Researchers identify a molecule critical to functional brain rejuvenation
A new study has identified a molecule called ten-eleven-translocation 1 (TET1) as a necessary component in the repair of myelin, which protects nerves and facilitates accurate transmission of electrical signals. The discovery could have important impli…
Studies reveal skull as unexpected source of brain immunity
Researchers have discovered that the immune cells that protect the brain and spinal cord come primarily from the skull. The finding opens up the possibility of developing therapies to target such cells as a way to prevent or treat brain conditions.
Brain disease research reveals differences between sexes
Scientists highlight a growing body of research suggesting sex differences play roles in how patients respond to brain diseases, as well as multiple sclerosis, motor neuron disease, and other brain ailments. They are urging their colleagues to remember…
Brain’s ‘wiring insulation’ as major factor of age-related brain deterioration
A new study has identified that one of the major factors of age-related brain deterioration is the loss of a substance called myelin. Myelin acts like the protective and insulating plastic casing around the electrical wires of the brain – called axons….