Women with multiple sclerosis (MS) may not be at a higher risk of pregnancy complications like gestational diabetes, emergency cesarean section or stillbirth than women who do not have the disease, according to a new study.
New research finds connection: Inflammation, metabolism and scleroderma scarring
A new study finds that NAD+ break down leads to multi organ scarring, providing now a previously undiscovered pathogenic role of the enzyme CD38 in disease scarring.
Study finds COVID-19 attack on brain, not lungs, triggers severe disease in mice
Researchers have found that infecting the nasal passages of mice with the virus that causes COVID-19 led to a rapid, escalating attack on the brain that triggered severe illness, even after the lungs were successfully clearing themselves of the virus.
Research suggests development of antiviral therapies to treat multiple sclerosis
Scientists have uncovered new clues implicating a type of herpes virus as the cause of a central nervous system disease in monkeys that’s similar to multiple sclerosis in people. By linking two specific T cells to the loss of myelin, scientists say the…
Compound protects myelin, nerve fibers
A compound appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord. The new research in a mouse model advances earlier work to develop the compound – known as sobetirome – that has alrea…
Gene therapy strategy found effective in mouse model of hereditary disease TSC
Patients with a genetic disorder called tuberous sclerosis complex have noncancerous tumors growing in numerous organs, and their treatment options are limited. A gene therapy strategy effectively treated mice that express one of the mutated genes that…
Multiple sclerosis as the flip side of immune fitness
About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study has now shown how this genetic predisposition contributes to the development of the autoimmune disease multiple sclerosis in combination with environmental factors…
Simple sugar possible therapy for repairing myelin in multiple sclerosis
N-acetylglucosamine, a simple sugar found in human breast milk and sold as an over-the-counter dietary supplement in the United States, promotes myelin repair in mouse models and correlates with myelination levels in multiple sclerosis patients, accord…
Cashew shell compound appears to mend damaged nerves
In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team reports today.
MS drug may be used to inhibit HIV infection and reduce latent reservoir
A multiple sclerosis drug may be used to block HIV infection and reduce the latent reservoir, according to new research.