Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term. In some cases the tumors disappear…
Benefits of early intervention in autoimmune diseases
Complex autoimmune diseases affecting various organ systems remain one of the greatest medical challenges in spite of immense advances in treatment. In particular, the diffuse symptoms at the early stage of complex autoimmune diseases make it hard to d…
New potential factor contributing to severity of COVID-19 identified
Researchers have identified a protein that may critically contribute to severe forms of COVID-19.
Scientists develop artificial intelligence method to predict anti-cancer immunity
Researchers and data scientists have developed an artificial intelligence technique that can identify which cell surface peptides produced by cancer cells called neoantigens are recognized by the immune system.
Innate immune response may predict COVID-19 severity
Combined measurements of granulocytes and well-known biomarkers in the blood can predict the severity of COVID-19, according to a new study. The results may eventually contribute to more tailored treatments for COVID-19 patients.
Infection hinders blood vessel repair following traumatic brain or cerebrovascular injuries
Traumatic brain injury (TBI) and other injuries to blood vessels in the brain, like stroke, are a leading cause of long-term disability or death. Researchers have found a possible explanation for why some patients recover much more poorly from brain in…
New avenue for study of diseases like multiple sclerosis
A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination — when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between ne…
Immune cells in the brain share the work
To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. However, in certain mutations that can cause Parkinson’s disease, this cooperation is impaired.
Microneedle patch delivers COVID-19 DNA vaccine; doesn’t require cold storage
Researchers have developed a microneedle patch that delivers a COVID-19 DNA vaccine into the skin, causing strong immune responses in cells and mice. Importantly, the patch can be stored for over 30 days at room temperature.
Researchers use exosome-based strategy to block HIV in mice
Researchers used exosomes, tiny nanoparticles capable of being taken up by cells, to deliver novel protein into the cells of mice infected with HIV. The protein attached to HIVs’ genetic material and prevented it from replicating, resulting in reduced …