Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different ‘program’ that makes them less effective than immune cells in patients whose cancers respond to these immune tr…
Scientists find a new way to reverse immune suppression in tumors
Malignant tumors can enhance their ability to survive and spread by suppressing anti-tumor immune cells in their vicinity, but a new study has uncovered a new way to counter this immunosuppressive effect.
Discovery highlights the complex lifestyles of frontline immune cells
Researchers have made a surprise discovery about how immune ‘sentinel’ cells are maintained, which could have implications for drugs in development for treating cancer.
Patients with multiple sclerosis show robust T-cell responses to mRNA COVID-19 vaccines
New research shows that mRNA COVID-19 vaccines are effective at inducing T-cell responses in multiple sclerosis patients who receive B cell-depleting infusions even if their antibody responses are diminished.
Cancer cells’ unexpected genetic tricks for evading the immune system
In a surprising new finding in mice, researchers have discovered that many genes linked to human cancer block the body’s natural defense against malignancies.
Discovery of rapid-response signaling platform suggests new path for blocking allergic inflammation
A recent study reveals new details about how the body’s type 2 innate immune response system works.
Biologists identify new targets for cancer vaccines
Vaccinating against certain cancer proteins can boost overall T cell response and help shrink tumors in mice, according to scientists. The findings could help researchers decide what proteins to include in cancer vaccines.
COVID-19 nasal vaccine candidate effective at preventing disease transmission, study shows
A nasal vaccine candidate for COVID-19 is showing good results in providing durable local immunity against inhaled pathogens.
Proteins that outwit emerging and re-emerging viruses
A family of proteins best known for their role in diminishing HIV infectivity may have the goods to outwit other emerging and re-emerging viruses, scientists have found.
New findings on B cells may improve vaccine design
Our bodies can fine-tune the immune response to an infection and make it proportional to the threat at hand. New research describes how B lymphocytes, the immune cells that make antibodies, choose between different cell fates to balance the magnitude o…