Experts in MS research suggest that cognitive rehabilitation is an effective approach to improving MS-related cognitive impairment.
New study sheds light on how an autoimmune disorder may underlie male infertility
Investigators have found that the absence of autoimmune regulator (Aire) in mice results in fertility problems similar to those affecting men with autoimmune polyendocrine syndrome type I (APS-1). Aire-dependent central tolerance plays a critical role …
Varying immune cell levels in canine brain tumors could provide therapeutic targets
A new study reveals that high-grade gliomas, or brain tumors, in dogs contained more immune cells associated with suppressing immune response than low-grade gliomas.
Sequential-combinatorial regimens can make treatment more effective for people with aggressive cancers
A new preclinical study suggests that treating people who have aggressive cancers, including melanoma, pancreatic and colorectal cancers, with immune checkpoint inhibitors, quickly followed with mutation-targeted therapy, can help overcome treatment re…
New approach identifies T cells in COVID-19 patients
T cells play a decisive role in fighting the coronavirus and preventing infected individuals from becoming seriously ill. They identify and fight the virus directly within the infected cells. Researchers have produced a precise profile of the T cells t…
Videos capture lethal progress of COVID-19 virus
Video images capture for the first time in live animals the inexorable spread of the COVID-19 virus, tracking the infection as it moved from the noses of mice to the lungs and other organs over the course of six days, in a new study.
Heat-controllable CAR T cells destroy tumors and prevent relapse in new study
New research builds on a body of work exploring remotely controlled cell therapies, in which the researchers can precisely target tumors, wherever they are in the body, with a local deposition of heat. The latest study shows the system cured cancer in …
Inhibitor drug entinostat ‘primes’ the body to better respond to anti-cancer treatment with immunotherapy
Combining a histone deacetylase inhibitor drug with immunotherapy agents has been deemed safe, and may benefit some patients with advanced cancers that have not responded to traditional therapy, according to results of a phase 1 clinical trial.
New research provides clues to developing better intranasal vaccines for COVID-19 and flu
While gut microbiota play a critical role in the induction of adaptive immune responses to influenza virus infection, the role of nasal bacteria in the induction of virus-specific adaptive immunity is less clear. New research explores the role of nasal…
Small protein protects pancreatic cells in model of type 1 diabetes
A new study has shown that treating type 1 diabetes-prone mice with the small protein MOTS-c prevented the immune system from destroying insulin-producing pancreatic cells, effectively preventing the onset of the autoimmune disease. The small protein t…