MS Wire

Researchers have found a way to reduce organ rejection following a transplant by using a special polymer to coat blood vessels on the organ to be transplanted. The polymer substantially diminished rejection of transplants in mice when tested. The disco…

A team of researchers has developed an immunotherapy strategy that can eliminate pancreatic tumors in mice. The new therapy, a combination of three drugs that boost the body’s immune defenses against tumors, is expected to enter clinical trials later t…

An immune signal promotes the production of energy-burning ‘beige fat,’ according to a new study. The finding may lead to new ways to reduce obesity and treat metabolic disorders.

Researchers found that a specific subtype of macrophages that originated from blood monocytes plays a key role in the hyper-inflammatory response in SARS-CoV-2 infected lungs, by performing single-cell RNA sequencing of bronchoalveolar lavage fluid cel…

Scientists have developed two complementary bladder models to study urinary tract infections (UTIs) caused by E. coli: bladder organoids and a bladder-on-a- chip. The two studies reveal how bacteria invade the bladder, and how they evade the immune sys…

Researchers identified an inhibitor that showed promise against metastatic castration-resistant prostate cancer cells. From there, they continued to untangle the web to discover multiple levels of cellular processes that were preventing the immune syst…

University of Maryland researchers discovered a way that Mycobacterium tuberculosis (Mtb), the bacterium that causes tuberculosis, can cause a person’s immune cells to lower their defenses. Specifically, they identified a gene in the bacterium that sup…

Treating obese mice with the cytokine known as TSLP led to significant abdominal fat and weight loss compared to controls. The animal model findings support the possibility that increasing sebum production via the immune system could be a strategy for …

Researchers have discovered the underlying genetic cause of a rare childhood disorder that mimics inflammatory bowel disease, a finding that may help researchers uncover the roots of a host of other inflammatory and autoimmune disorders.

A new study of cells shows that antibodies produced by the body in response to COVID-19 may be triggering a blood clotting response in patients with severe disease.