MS Wire

Scientists have developed a ‘nanobody’ – a small fragment of a llama antibody – that is capable of chasing out human cytomegalovirus (HCMV) as it hides away from the immune system. This then enables immune cells to seek out and destroy this potentially…

In a new study, scientists discover how the production of protective molecules known as specialized pro-resolving mediators is altered in patients with COVID-19.

Researchers have identified an immune protein tied to the rare neurodegenerative condition known as Niemann-Pick disease type C. The finding, made in mouse models, could offer a powerful new therapeutic target for Niemann-Pick disease type C, a conditi…

Older people appear to have fewer antibodies against the novel coronavirus, a new laboratory study suggests. With vaccine uptake slowing in Oregon and across United States, researchers say their findings underscore the importance of promoting vaccinati…

The parasites that cause severe malaria are well-known for the sinister ways they infect humans, but new research may lead to drugs that could block one of their most reliable weapons: interference with the immune response.

In a new study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease o…

Researchers have shown that the L452R mutation of the SARS-CoV-2 spike protein, which is common to two variants (Epsilon and Delta), is involved in cellular immunity evasion via the human leukocyte antigen (HLA) A24, and enhances viral infectivity.

Researchers have found that immunoglobulin A (IgA) deficiency leads to disruption of the ileal gut microbiota and increased inflammation in the ileum in mice. This suggests that IgA plays an important role in mucosal homeostasis by regulating the intes…

Researchers have discovered another functional autoantibody in COVID-19 patients that contributes to the disease’s development and the ‘firestorm’ of blood clots and inflammation it induces. The autoantibody makes it much harder for the body to degrade…

The second dose of a COVID-19 vaccine induces a powerful boost to a part of the immune system that provides broad antiviral protection, according to a new study.