Cancer cells can put the body’s immune cells into sleep mode. Immunotherapy can reverse this, but it doesn’t work for all patients and all cancer types. Researchers have now developed machine learning models that can predict if someone is likely to res…
A promising two-punch therapy for Langerhans cell histiocytosis
A novel combination therapy resulted in a significant decrease of disease burden in an animal model of LCH.
How a COVID-19 infection changes blood cells in the long run
New research suggests that a coronavirus infection alters the biomechanical properties of red and white blood cells, in some cases for months — a possible explanation for long COVID.
Looking at tumors through a new lens
A new study reveals vulnerabilities in recurrent glioblastoma, providing potential co-targets for enhancing neoadjuvant immune checkpoint blockade.
Targeted delivery of therapeutic RNAs only to cancer, no harm caused to healthy cells
The groundbreaking technology may revolutionize the treatment of cancer and a wide range of diseases and medical conditions.
Researchers discover unique ‘spider web’ mechanism that traps, kills viruses
Immunologists have discovered a previously unknown mechanism which acts like a spider web, trapping and killing pathogens such as influenza or SARS-CoV-2, the virus responsible for COVID-19.
Cell-based immunotherapy shows promise against melanoma
Researchers have shown in preclinical studies conducted in mice and human cells that a type of immunotherapy based on natural killer cells could be effective against solid tumors, starting with melanoma, a type of skin cancer that can be deadly if not …
Call to increase genetic diversity in immunogenomics
Historically, most large-scale immunogenomic studies – those exploring the association between genes and disease – were conducted with a bias toward individuals of European ancestry. Researchers are now calling to actively diversify the genetic resourc…
COVID-19 vaccine generates immune structures critical for lasting immunity
The first two COVID-19 vaccines authorized for emergency use by the U.S. Food and Drug Administration (FDA) employed mRNA technology, which had never before been used in FDA-approved vaccines. A new study has found evidence that the immune response to …
Connective tissue protein fights bacterial infection
A connective tissue protein known to support the framework of organs also encourages immune responses that fight bacterial infections, while restraining responses that can be deadly in the condition called sepsis.