Researchers have investigated the role that hormones play in male and female inflammatory responses. In a new study, he found that testosterone may protect against stomach inflammation.
AI helps predict treatment outcomes for patients with diseased dental implants
Peri-implantitis, a condition where tissue and bone around dental implants becomes infected, besets roughly one-quarter of dental implant patients, and currently there’s no reliable way to assess how patients will respond to treatment of this condition.
New findings linking brain immune system to psychosis
New research suggests a link between psychosis and a genetic change that affects the brain’s immune system. The study may impact the development of modern medicines for bipolar disorder or schizophrenia.
In the blood: Which antibodies best neutralize the coronavirus in COVID-19 patients?
Blood tests to detect antibodies against SARS-CoV-2, the virus that causes COVID-19, are an important tool for diagnosing the disease, developing potential treatments, and checking vaccine efficacy. Although such tests are available, we have very littl…
Gene therapy restores immune function in children with rare immunodeficiency
An investigational gene therapy can safely restore the immune systems of infants and children who have a rare, life-threatening inherited immunodeficiency disorder, according to new research. The researchers found that 48 of 50 children who received th…
Researchers discover regulatory pathway that blocks immune response against cancer
Researchers show that TIM-3 inhibits the STING signaling pathway in dendritic cells, thereby blocking their ability to elicit an immune response.
New research outlines a critical driver in an immune cell’s defense against melanoma
Researchers have found critical new insights into how cells defend against melanoma. The team describes how an enzyme called nicotinamide phosphoribosyltransferase, or NAMPT, initiates antitumor activity. The researchers suggest that new therapies stre…
How to predict severe influenza in hospitalized patients
Researchers have identified predictors of both severe disease and recovery in hospitalized influenza patients, finding that the immune system works in concert to fight influenza.
Biomarker detects severe COVID-19 early on
Severe cases of COVID-19 can now be detected at an early stage. Researchers have identified the first biomarker that can reliably predict which patients will develop severe symptoms. This can help to improve the treatment of severe cases of COVID-19.
TB immune response discovery could significantly reduce disease harm
A pioneering study has discovered the presence of a harmful inflammatory protein in patients with symptomatic tuberculosis (TB). Researchers say, by targeting the IL-17 cytokine, a component produced naturally by the immune system in response to infect…