Researchers have identified more than 250 ‘severity associated’ proteins in the worst cases of COVID-19. These findings could help researchers identify the mechanisms that cause severe COVID-19.
Intranasal influenza vaccine enhances immune response and offers broad protection
An influenza vaccine that is made of nanoparticles and administered through the nose enhances the body’s immune response to influenza virus infection and offers broad protection against different viral strains, according to new research.
Scientists invent cryomicroneedles for intradermal therapeutic cell delivery
Scientists recently developed a new generation of microneedles technology which allows the intradermal delivery of living cells in a minimally invasive manner. Their experiment showed that vaccination using therapeutic cells through this ground-breakin…
Engineering T cells to attack cancer broadly
This study builds on decades of work showing that the protein IL-24 attacks cancer broadly, and is the first to deliver the protein using T cells. This approach is in contrast to CAR-T cells, which are built to recognize proteins on the surface of canc…
Shortage of DNA building blocks in the cell releases mitochondrial DNA
Mitochondria are the energy suppliers of our body cells. These tiny cell components have their own genetic material, which triggers an inflammatory response when released into the interior of the cell. The reasons for the release are not yet known, but…
Prior SARS-CoV-2 infection boosts response to variants after first vaccine dose
A single dose of vaccine boosts protection against SARS-CoV-2 coronavirus variants, but only in those with previous COVID-19, a study has found.
New atlas of genetic function maps complexities of immune system and immune diseases
A new genetic database for autoimmune and autoinflammatory diseases will allow experts to more deeply understand how immune disorders develop and plan future drug discovery projects. Scientists also hope this atlas of immune-related genome data may eve…
How meningitis-causing bacteria may sense fever to avoid immune killing
Researchers have discovered a mechanism through which meningitis-causing bacteria can evade our immune system. In laboratory tests, they found that Streptococcus pneumoniae and Haemophilus influenzae respond to increasing temperatures by producing safe…
How SARS-CoV-2 hijacks human cells to evade immune system
Researchers discovered one way in which SARS-CoV-2 hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.
New, rapid CRISPR/Cas9 method identifies key genes in zebrafish spinal cord regeneration
A new, rapid screening approach uses CRISPR/Cas9 technology to identify immune system-related genes that play a crucial role in repairing zebrafish spinal cord injuries.