Duchenne muscular dystrophy (DMD) is the most common muscle disease in children and is passed on by X-linked recessive inheritance. Characteristic is a progressive muscular atrophy. Researchers have found a connection between dystrophic muscles and the…
Mechanism underlying cancer cells’ immune evasion
Researchers have discovered how brain cancer cells increase production of a key protein that allows them to evade the body’s immune system. The study suggests that targeting this cellular pathway could help treat the deadly brain cancer glioblastoma, a…
Researchers identify RNA molecule that helps lung cancer cells evade immune system
Researchers have identified a non-coding RNA molecule that helps lung cancer cells proliferate and avoid being killed by the body’s immune cells. The study suggests that targeting this RNA molecule could boost the effectiveness of immunotherapies that …
New tool identifies which cancer patients are most likely to benefit from immunotherapy
A new diagnostic tool that can predict whether a cancer patient would respond to immunotherapy treatment has been developed. This advance in precision medicine will allow clinicians to tailor treatments specifically to patients and avoid treatment path…
Transplanted brown-fat-like cells hold promise for obesity and diabetes
A potential therapy for obesity would transplant HUMBLE (human brown-like) fat cells, human white fat cells that have been genetically modified using CRISPR to become similar to heat-generating brown fat cells.
Unique HIV reservoirs in elite controllers
Unlike ART-treated individuals, elite controllers’ viral reservoirs appear to be incapable of being reactivated. This likely helps the elite controllers maintain spontaneous, drug-free control of HIV.
Tag team gut bacteria worsen symptoms of multiple sclerosis
Researchers have discovered that a particular combination of microorganisms in the gut can worsen symptoms in a mouse model of multiple sclerosis. The study shows that two specific gut bacteria enhance the activity of immune cells that attack the body’…
New blood, new hope: Transfusions protect the brain from stroke damage
Neuroscientists found that blood substitution therapy rescues the brains of mice from ischemic damage, a potential breakthrough in stroke therapy.
Most adults with lupus or common types of arthritis have similar risks of getting admitted to hospital as other COVID-19 patients
Most adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to dampen their altered immune system, the cause of their disease.
Flexible targets help immune system make finely-tuned antibodies
An in-depth study of how the immune system generates effective antibodies provides new insights for vaccine design.