Researchers report that adding a small molecule to a chimeric antigen receptor-T (CAR-T) cell therapy can help immune system T cells to effectively attack solid tumors, such as breast cancers. The boost helps recruit more immune cells into battle at th…
Blood vessel cells implicated in chronic inflammation of obesity
When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with obesity. Now, scientists have discovered a t…
New research may explain severe virus attacks on the lungs
In some cases, immune cells in the lungs can contribute to worsening a virus attack. In a new study, researchers describe how different kinds of immune cells, called macrophages, develop in the lungs and which of them may be behind severe lung diseases…
Potential new RX strategy for stroke
new research reports that a combination of a new drug and selected DHA derivatives is more effective in protecting brain cells and increasing recovery after stroke than a single drug.
Sustained cellular immune dysregulation in individuals recovering from COVID-19
Observational clinical research of COVID-19 patients can help clinicians better understand how the previously unknown SARS-CoV-2 virus acts, and findings from this research can better inform treatment and vaccine design.
Gut cells sound the alarm when parasites invade
When the parasite Cryptosporidium enters the body, it’s cells in the intestines that first recognize the invader, triggering an early immune response, according to a new study. A leading cause of diarrheal disease in young children globally, the parasi…
Discovery about how cancer cells evade immune defenses inspires new treatment approach
Researchers have learned how chromosomal instability allows cancer cells to avoid immune defenses and metastasize (spread). The discovery opens up potential new avenues for treatment.
Protein tells developing cells to stick together
Scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development. How tightly cells clump together, known as cell adhesion, appears to be enabled by a protein…
New class of antibiotics active against a wide range of bacteria
Scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing of pan drug-resistant bacterial pathogens with a simultaneous rapid immune response for combating antimicrobial resistance (AMR).
Molecular reporters expose the allies of the brain tumor
Until recently, it was unclear how and why cancer cells adapt to their environment. A team has now developed a technology that can be used to observe the molecular processes in living cells.