University of Maryland researchers discovered a way that Mycobacterium tuberculosis (Mtb), the bacterium that causes tuberculosis, can cause a person’s immune cells to lower their defenses. Specifically, they identified a gene in the bacterium that sup…
Mice treated with this cytokine lose weight by ‘sweating’ fat
Treating obese mice with the cytokine known as TSLP led to significant abdominal fat and weight loss compared to controls. The animal model findings support the possibility that increasing sebum production via the immune system could be a strategy for …
Rare disorder offers roadmap for understanding roots of inflammatory disease
Researchers have discovered the underlying genetic cause of a rare childhood disorder that mimics inflammatory bowel disease, a finding that may help researchers uncover the roots of a host of other inflammatory and autoimmune disorders.
Blood clots in people with severe COVID-19 may be related to abnormal antibody response
A new study of cells shows that antibodies produced by the body in response to COVID-19 may be triggering a blood clotting response in patients with severe disease.
T cell response not critical for immune memory to SARS-CoV-2 or recovery from COVID-19, study finds
New research conducted in monkeys reveals that T cells are not critical for the recovery of primates from acute COVID-19 infections.
New breakthrough to help immune systems in the fight against cancer
New research has identified potential treatment that could improve the human immune system’s ability to search out and destroy cancer cells within the body. Scientists have identified a way to restrict the activity of a group of cells which regulate th…
New understanding of cell stability with potential to improve immune cell therapies
Researchers have developed two solutions with potential to overcome a key clinical limitation of immune cell therapies.
Brain-repair discovery could lead to new epilepsy treatments
Researchers have discovered a previously unknown repair process in the brain that they hope could be harnessed and enhanced to treat seizure-related brain injuries.
New insights into immune responses to malaria
Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically.
Advanced bladder cancers respond to immunotherapy regardless of gene mutation status
Researchers report a study has demonstrated that patients with advanced bladder cancers whose tumors have a mutated FGFR3 gene respond to immunotherapy in a manner that is similar to patients without that mutation. This discovery runs counter to previo…