New research conducted in monkeys reveals that T cells are not critical for the recovery of primates from acute COVID-19 infections.
New breakthrough to help immune systems in the fight against cancer
New research has identified potential treatment that could improve the human immune system’s ability to search out and destroy cancer cells within the body. Scientists have identified a way to restrict the activity of a group of cells which regulate th…
New understanding of cell stability with potential to improve immune cell therapies
Researchers have developed two solutions with potential to overcome a key clinical limitation of immune cell therapies.
Brain-repair discovery could lead to new epilepsy treatments
Researchers have discovered a previously unknown repair process in the brain that they hope could be harnessed and enhanced to treat seizure-related brain injuries.
New insights into immune responses to malaria
Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically.
Advanced bladder cancers respond to immunotherapy regardless of gene mutation status
Researchers report a study has demonstrated that patients with advanced bladder cancers whose tumors have a mutated FGFR3 gene respond to immunotherapy in a manner that is similar to patients without that mutation. This discovery runs counter to previo…
‘Missing self’ contributes to organ rejection after transplantation
After kidney transplantation, natural killer cells of the recipient become active because they miss ‘self’ proteins on donor cells. These cells contribute to organ rejection, in addition to traditional modes of rejection involving T cells and antibodies.
‘Good cholesterol’ may protect liver
The body’s so-called good cholesterol may be even better than we realize. New research suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury. This HDL protects the liver by blocking i…
Cell-analysis technique could combat tuberculosis
Researchers have developed a way to analyze how individual immune cells react to the bacteria that cause tuberculosis. It could pave the way for new vaccine strategies and provide insights into fighting other infectious diseases.
Structural biology provides long-sought solution to innate immunity puzzle
Researchers report the first structural confirmation that endogenous — or self-made — molecules can set off innate immunity in mammals via a pair of immune cell proteins called the TLR4-MD-2 receptor complex. The work has wide-ranging implications fo…